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Anterior chamber paracentesis to improve diagnosis and treatment of infectious uveitis in South Africa

Erik Schaftenaar, Karin A Lecuona, G Seerp Baarsma, Christina Meenken, Georges Verjans, James A McIntyre, Remco P H Peters

Abstract


Infectious uveitis is a significant cause of blindness in South Africa, especially among HIV-infected individuals. The visual outcome of uveitis depends on early clinical and laboratory diagnosis to guide therapeutic intervention. Analyses of aqueous humor obtained by anterior chamber paracentesis direct the differential diagnosis in infectious uveitis. However, although safe and potentially cost-effective, diagnostic anterior chamber paracentesis is not common practice in ophthalmic care across Africa. We draw attention to this important procedure, which could improve the diagnosis and prognosis of infectious uveitis. 


Authors' affiliations

Erik Schaftenaar, Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands; Rotterdam Eye Hospital, The Netherlands; Anova Health Institute, Tzaneen, South Africa

Karin A Lecuona, Department of Ophthalmology, Groote Schuur Hospital and Faculty of Health Sciences, University of Cape Town, South Africa

G Seerp Baarsma, Rotterdam Ophthalmic Institute, The Netherlands

Christina Meenken, VU University Medical Center, Amsterdam, The Netherlands

Georges Verjans, Herpes Research Group, Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands

James A McIntyre, Anova Health Institute, Johannesburg, South Africa; School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, South Africa

Remco P H Peters, Anova Health Institute, Johannesburg, South Africa; Department of Medical Microbiology, Faculty of Health Sciences, University of Pretoria, South Africa

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Keywords

Infectious uveitis; Anterior chamber paracentesis; Polymerase chain reaction; Goldmann-Witmer coefficient; South Africa

Cite this article

South African Medical Journal 2015;105(8):628-630. DOI:10.7196/SAMJnew.7816

Article History

Date submitted: 2015-03-06
Date published: 2015-09-22

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