Correspondence

Paediatric chemoprophylaxis for child contacts of patients with drug-resistant tuberculosis: Are current guidelines effective in preventing disease?

Nesri Padayatchi, Naressa Naidu

Abstract


The World Health Organization estimates that there were 480 000 new cases of multidrug-resistant tuberculosis (MDR-TB) in 2013. Alarmingly, 40% of MDR-TB cases for which second-line drug susceptibility test results were reported originated in South Africa (SA). This has important implications in vulnerable pop- ulations, such as children, where infection with drug-resistant strains of TB are usually attributable to transmission rather than acquisition of resistance. 


Authors' affiliations

Nesri Padayatchi, South African Medical Research Council (SAMRC)/Centre for the AIDS Programme of Research in South Africa (CAPRISA) HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

Naressa Naidu, South African Medical Research Council (SAMRC)/Centre for the AIDS Programme of Research in South Africa (CAPRISA) HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

Full Text

PDF (60KB)

Keywords

Drug-resistant tuberculosis; Paediatric; Chemoprophylaxis

Cite this article

South African Medical Journal 2015;105(5):328-329. DOI:10.7196/SAMJ.9500

Article History

Date submitted: 2015-02-17
Date published: 2015-05-27

Article Views

Abstract views: 1396
Full text views: 601

Comments on this article

*Read our policy for posting comments here