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Culture-negative endocarditis due to Bartonella quintana

Vineshree Mischka Moodley, Tienie T S Zeeman, C H Johan van Greune, Craig Corcoran


Bartonella spp. was first described as a possible cause of culture-negative endocarditis in 1993, and has since emerged as a significant cause of this condition worldwide. We describe a complicated case of culture-negative endocarditis in an immune-competent male patient, which was confirmed on resected heart valves to have been caused by Bartonella quintana by broad-range 16S ribosomal RNA polymerase chain reaction. The objective of this report is to highlight the clinical, diagnostic and therapeutic challenges of Bartonella endocarditis.

Authors' affiliations

Vineshree Mischka Moodley, Ampath National Laboratory Services, Cape Town, South Africa

Tienie T S Zeeman, Netcare N1 City Hospital, Cape Town, South Africa

C H Johan van Greune, Ampath National Laboratory Services, Cape Town, South Africa

Craig Corcoran, Molecular Biology Unit, Ampath National Reference Laboratory, Pretoria, South Africa

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Endocarditis; Bartonella quintana

Cite this article

South African Medical Journal 2016;106(5):470-471. DOI:10.7196/SAMJ.2016.v106i5.9062

Article History

Date submitted: 2014-10-21
Date published: 2016-04-19

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