Research

Fresh-frozen plasma use in a South African tertiary hospital

Adele Visser, Annelize Geldenhuys, Samantha du Preez, Annemarie van de Vyver

Abstract


Despite available guidelines on indications for fresh-frozen plasma (FFP) transfusion, inappropriate use is increasing worldwide. We evaluated FFP administration to patients admitted to the Steve Biko Academic Hospital over 4 months, including indications for use and completeness of requisition forms. Transfusions were considered inappropriate for 39.5% of units administered. Of request forms submitted, only 22% had sufficient information for the blood transfusion services of the indication for transfusion. Transfusion with FFP is a medical intervention that carries risks and should be undertaken with care. Although this study was conducted in one centre, it is evident that clinicians’ lack of knowledge of the indications for administration of FFP is widespread. Intervention is necessary to improve patient outcomes and reduce expenditure.

Authors' affiliations

Adele Visser, Division of Clinical Pathology, Department of Medical Microbiology, University of Pretoria, and National Health Laboratory Service (Tshwane Academic Division), Pretoria

Annelize Geldenhuys, Department of Haematology, University of Pretoria, and National Health Laboratory Services (Tshwane Academic Division), Pretoria

Samantha du Preez, Department of Haematology, University of Pretoria, and National Health Laboratory Services (Tshwane Academic Division), Pretoria

Annemarie van de Vyver, Department of Internal Medicine, Kalafong Hospital, and University of Pretoria

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Keywords

Fresh frozen plasma; Audit

Cite this article

South African Medical Journal 2012;102(6):366-367.

Article History

Date submitted: 2011-07-17
Date published: 2012-05-08

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