The Global Antibiotic Resistance Partnership

Part IV. GARP: Human infections and antibiotic resistance

P Crowther-Gibson, N Govender, D A Lewis, C Bamford, A Brink, A von Gottberg, K Klugman, M du Plessis, A Fali, B Harris, K Keddy, M Botha

Abstract


South Africa has a high burden of infectious diseases, including a large portion that are of bacterial origin. This section reviews the national burden of disease and levels of antibiotic resistance in common bacterial infections in the human population. The consequences of resistance on clinical outcomes, through either treatment failures or the development of more virulent infections, are largely unknown. The full impact of antibiotic resistance on health in South Africa therefore remains to be assessed.

Authors' affiliations

P Crowther-Gibson, Wits; NHLS

N Govender,

D A Lewis,

C Bamford,

A Brink,

A von Gottberg,

K Klugman,

M du Plessis,

A Fali,

B Harris,

K Keddy,

M Botha,

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Keywords

HIV/AIDS; Tuberculosis; Antimicrobial resistance; Diarrhea; Respiratory infection; Bacterial disease; Sexually-transmitted infections; Hospital-acquired infections; Microbiology; Surveillance; Antibiotics; antibiotic (antimicrobial) resistance; pneumonia

Cite this article

South African Medical Journal 2011;101(8):567-578.

Article History

Date submitted: 2011-06-24
Date published: 2011-07-28

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