Original articles
Nurses at risk for occupationally acquired blood-borne virus infection at a South African academic hospital
Abstract
Methods. We studied 170 predominantly black nurses. Their blood was tested for the presence of active or past HBV infection using appropriate immunoassays, HCV infection by chromatographic immunoassays confirmed by polymerase chain reaction assays, and HIV using a rapid test confirmed by enzyme-linked immunosorbent assays.
Results. Serum of 89 (52.4%) nurses was positive for hepatitis B surface antibody (anti-HBs). Of these nurses 18 said that they had not received the vaccine; the serum of 9 of these was positive for anti-hepatitis B core antibody (anti-HBc) as well as anti-HBs, indicating natural infection with the virus. Of the nurses positive for anti-HBs, 89 were tested for anti-HBc; 28.2% tested positive for anti-HBc. Three nurses gave dates of immunisation that fell outside of their nursing careers; 3 (1.8%) were actively infected with the virus; 2 (1.8%) were infected with HCV; 10 nurses (5.9%) were positive for HIV.
Conclusion. Nurses at this academic hospital remain at high risk of work-related HBV infection.
Authors' affiliations
T Mosendane, Departments of Medicine and Gastroenterology, University of the Witwatersrand, and Johannesburg Academic Hospital, Johannesburg, South Africa
M C Kew, Departments of Medicine, University of the Witwatersrand, Johannesburg and University of Cape Town, South Africa
R Osih, Departments of Medicine and Gastroenterology, University of the Witwatersrand, and Johannesburg Academic Hospital, Johannesburg, South Africa
A Mahomed, Departments of Medicine and Gastroenterology, University of the Witwatersrand, and Johannesburg Academic Hospital, Johannesburg, South Africa
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Article History
Date published: 2012-02-23
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