Cytomegalovirus antibodies amongst healthy blood donors at Lagos University Teaching Hospital (Luth)
METHODS: A cross-sectional study was carried out amongst clients attending the blood donor clinic at LUTH who were recruited consecutively. A total of 5mls of blood sample was collected per consenting participant. The serum obtained was assayed for CMV IgG/IgM using an enzyme linked immunosorbent assay (ELISA) based Kit .Statistical analysis of results was done using the following computer soft wares , Statistical Package for Social Sciences (SPSS11.0), Microsoft excel, file maker Pro, and Epi-Info 6.0 as appropriate.
RESULTS: A total of 122 healthy donors were recruited for the study. The results showed 96% of the donors were IgG anti-CMV positive whilst 19.5% were IgM anti-CMV positive. Previous history of blood transfusion was not significantly related to CMV positivity.
CONCLUSION: The seroprevalence of CMV appears to be very high in this environment amongst healthy blood donors. The presence of IgM anti-CMV in a quarter of Blood donors is of clinical relevance particularly in the event of transfusion of neonates and immunocompromised persons in a society where CMV screening is not a routine pre-transfusion test
KEY WORDS: CMV IgG/IgM, healthy blood donors, Elisa
Akinsegun Abduljaleel Akinbami, University
Akanni Sulayman Akanmu, University
Titilope A Adeyemo, University
Kikelomo Ololade Wright, University
Mobolaji Olufemi Dada, University
Adedoyin O Dosunmu, University
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Date published: 2009-07-07
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