Festschrift: Professor Hendrik Johannes Koornhof

Chronic Mucocutaneous Candidiasis. An Immunological Mystery

Arthur Ronald Rabson

Abstract


CMC refers to a group of disorders, which have in common recurrent and persistent infections of the skin, nails and mucous membranes by Candida albicans and occasionally other Candida species. A proportion of these patients show an associated endocrinopathy as part of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) syndrome. Many of the patients however, are not associated with endocrinopathy and demonstrate a variety of defects of T-cell or antigen presenting cell defects leading to abnormal cell mediated responses to Candida albicans.

Author's affiliations

Arthur Ronald Rabson, Tufts-New England Medical Center

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Keywords

Candidiasis

Cite this article

South African Medical Journal 2007;97(11):1190.

Article History

Date submitted: 2007-07-05
Date published: 2007-11-23

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